EC Number   |
Reaction |
Reference |
|---|
    4.2.3.12 | 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate |
catalyses triphosphate elimination and an intramolecular redox reaction in the presence of Mg2+. Identified in human liver. The product is 6-pyruvoyltetrahydrobiopterin |
- |
| 4.2.3.12 | 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate |
mechanism |
648557 |
| 4.2.3.12 | 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate |
the enzyme catalyzes the elimination of triphosphate as well as a series of tautomerization reactions. Incorporation of protons into positions C6 and C3' of the product |
648572 |
