EC Number |
Reaction |
Reference |
---|
4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine = (S)-norcoclaurine + H2O |
- |
- |
4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine = (S)-norcoclaurine + H2O |
the reaction makes a 6-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates |
- |
4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine = (S)-norcoclaurine + H2O |
the reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates, the product is the precursor of the benzylisoquinoline alkaloids in plants, the enzyme, formerly known as (S)-norleudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl)benzene-1,2-diol + (di-3,4-hydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline, but this alkaloid has not been found to occur in plants, cooperativity between substrate binding sites |
653569 |
4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine = (S)-norcoclaurine + H2O |
the reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates, the product is the precursor of the benzylisoquinoline alkaloids in plants, the enzyme, formerly known as (S)-norleudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl)benzene-1,2-diol + (di-3,4-hydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline, but this alkaloid has not been found to occur in plants, iso-ordered bi-uni mechanism with 4-hydroxyphenylacetaldehyde binding before dopamine |
652296 |