EC Number |
Reaction |
Reference |
---|
4.1.1.33 | ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 |
catalytic mechanism of this rare type of decarboxylase, the enzyme is bifunctional showing the reactions of diphosphomevalonate decarboxylase (EC 4.1.1.33) and mevalonate 3-kinase (EC 2.7.1.185), overview |
-, 759486 |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 |
mechanism |
4371 |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 |
ordered sequential mechanism with mevalonate 5-diphosphate as the first substrate to bind to the enzyme |
4385 |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 |
sequential mechanism |
4374 |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2 |
thiophosphoryl group transfer proceeds with inversion of configuration at phosphorus |
4379 |