EC Number |
Reaction |
Reference |
---|
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
- |
- |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
3 features are important for catalytic performance: i. a catalytic triad, ii. anoxyanion hole, and iii. the halide-stabilizing residues, which are not conserved among different haloalkane dehalogenases, active site structure, Asn38 is involved, SN2 reaction mechanism, modeling, overview |
-, 654629 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
3 features are important for catalytic performance: i. a catalytic triad, ii. anoxyanion hole, and iii. the halide-stabilizing residues, which are not conserved among different haloalkane dehalogenases, active site structure, Asn41 is involved, SN2 reaction mechanism, modeling, overview |
654629 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
3 features are important for catalytic performance: i. a catalytic triad, ii. anoxyanion hole, and iii. the halide-stabilizing residues, which are not conserved among different haloalkane dehalogenases, active site structure, Glu56 is involved, SN2 reaction mechanism, modeling, overview |
-, 654629 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
activation energy of reaction 59.5 kJ/mol |
-, 670729 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds |
655080 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
alpha/beta hydrolase with catalytic triad, i.e. nucleophile (Asp124)-histidine (H289)-acid (Asp260), during catalytic reaction |
-, 247091, 247093, 247094, 247096, 247101 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
Asp103, Glu127 and His280 are involved in the catalytic reaction, and two H-bond donating residues, Asn38 and Trp104, are involved in stabilization of a halogen group of the substrate |
-, 719460 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
catalytic mechanism |
247086 |
3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
catalytic nucleophile Asp108, which is the most disordered catalytic residue, catalytic base His272, structure-based reaction mechanism, active site structure, overview |
-, 654762 |