EC Number |
Reaction |
Reference |
---|
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
- |
- |
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
active site sequence HEIGHSFGLEHE 150 amino acid residues from the N-terminus of the protein |
650725 |
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
active site sequence HEXXHXXGXXHD |
652191 |
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
enzyme is a hemostatic factor |
650714 |
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
the cysteine-rich/spacer domains are essential for the proteolytic activity |
650712 |
3.4.24.87 | The enzyme cleaves the von Willebrand factor at bond Tyr842-/-Met843 within the A2 domain |
the spacer region is essential, while the C-terminal thrombospondin type 1 motif and the CUB domain are dispensable in vitro |
652431 |