EC Number   |
Reaction |
Reference |
|---|
   3.4.21.119 | Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin |
active site is located in the cleft between two beta-barrel domains, with an ordered kallikrein loop conformation close to it |
647371 |
| 3.4.21.119 | Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin |
enzyme is a serine protease |
647371, 647372, 647373 |
| 3.4.21.119 | Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin |
preference for Xaa-Arg-Arg- motif |
647359 |
| 3.4.21.119 | Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin |
substrate binding |
647371 |
