EC Number |
Reaction |
Reference |
---|
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
catalytic mechanism involving the Zn2+ ion and residue Glu270 with ester or protein substrates, the tetrahydrate transition state is stabilized by Arg127, overview |
668360 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
conceptual model of relationship between activity, mechanism and conformational mobility |
36356 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
correlations between mechanism, kinetics, and structure, intermediates and rate-determining steps |
36317 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
cryospectrokinetic characterization of intermediates, time-course of reaction |
36346 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
evidence for acyl-enzyme intermediates |
36352 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
evidence of general base pathway |
36353 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
mechanism |
36317, 36319, 36322, 36341, 36344, 36345, 36346, 36349, 36352, 36353, 36356, 36361 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
mechanisms elucidated from complex with inactivator 2-benzyl-3-iodo-propanoic acid |
36361 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
molecular dynamics characterization of active cavity |
36359 |
3.4.17.1 | release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro |
pK values of active site residues, analysis of kinetics and mechanism under alkaline conditions |
36349 |