EC Number   |
Reaction |
Reference |
|---|
    2.9.1.1 | L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec + phosphate |
substrate binding and reaction mechanism |
693212 |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec + phosphate |
the formyl group of pyridoxal phosphate forms a Schiff base with the alpha-amino group of L-Ser with the subsequent 2,3-elimination of a water molecule and the generation of an aminoacrylyl-tRNASecUCA intermediate |
22912 |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec + phosphate |
tRNA is bound near the margin of the dimeric subunits, appears to bind only one seryl-tRNA Sec per dimer |
22915 |
