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EC Number	Reaction	Commentary	Reference
2.7.7.13	GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose	bifunctional enzyme with both phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activity	642878
2.7.7.13	GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose	enzyme has both phosphomannose isomerase, i.e. PIM, and guanosine 5'-diphospho-D-mannose pyrophosphorylase, i.e. GMP, activity	2824
2.7.7.13	GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose	PMI and GMP activities are most probably located in catalytically distinct domains	2823

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Release 2023.1 (January 2023)