EC Number |
Reaction |
Reference |
---|
2.7.2.2 | ATP + carbamate = ADP + carbamoyl phosphate |
(1a) |
- |
2.7.2.2 | ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O |
comparison of carbamate kinases and carbamoyl phosphate synthases |
642233 |
2.7.2.2 | ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O |
mechanism |
-, 642219, 642223, 642225, 642226, 642229 |
2.7.2.2 | ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O |
overall reaction |
- |
2.7.2.2 | ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O |
random type reaction mechanism |
642221 |
2.7.2.2 | ATP + NH3 + hydrogencarbonate = ADP + carbamoyl phosphate + H2O |
the protein residues involved in ligand binding, together with a model of the transition state, suggest that catalysis follows an in-line, predominantly dissociative, phosphotransfer reaction mechanism, and that closure of the flexible auxiliary domain is required to protect the transition state from bulk solvent. Model of the transition state, overview |
739466 |
2.7.2.2 | NH3 + hydrogencarbonate = carbamate + H2O |
(1b), spontaneous |
- |