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EC Number Reaction Commentary Reference
Show all pathways known for 2.7.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.36ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate catalytic reaction mechanism, substrate binding structure involves key residue His25 in a deep cavity lined by highly conserved residues, Lys18, Asp155, Val202, and Thr283 are involved in catalysis 672817
Show all pathways known for 2.7.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.36ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate role for residue E193 in interacting with the cation of the MgATP substrate, and for D204 as the catalytic base that facilitates deprotonation of the C5 hydroxyl of mevalonic acid 698708
Show all pathways known for 2.7.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.36ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate sequential mechanism 641432, 663334
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