EC Number |
Reaction |
Reference |
---|
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
active sites pointing away from each other, a long arm from each monomer subunit wraps around the other subunit |
638375 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
modelling of enzyme-5-phospho-alpha-D-ribose 1-diphosphate complex |
638375 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
ping pong steady state kinetic pattern, ordered bi-bi mechanism, model, no formation of the phosphoribosyl-enzyme intermediate predicted by classic ping pong kinetics |
638371 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
ping-pong reaction mechanism |
638363 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
Pro131 is of little importance for 5-phospho-alpha-D-ribose 1-diphosphate binding, but critical for binding of uracil to the enzyme-5-phospho-alpha-D-ribose 1-diphosphate complex |
638372 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
rapid-random equilibrium mechanism |
-, 638368 |
2.4.2.9 | UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
sequential reaction mechanism |
638372, 638374 |