EC Number   |
Reaction |
Reference |
|---|
    2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
3 binding sites between substrate and enzyme |
637540 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
active and substrate-binding sites, three-dimensional structures |
637551, 637555 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
catalytic mechanism |
637551, 637555 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
equilibrium-ordered reaction, 5'-methylthioadenosine is the first substrate to bind and 5-methylthioribose 1-phosphate is the first product to be released |
637528 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
ordered bisubstrate biproduct reaction with methylthioadenosine the first substrate to add and adenine the last product to leave the enzyme |
637536 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
phosphorolytic mechanism |
637526, 637527, 637528, 637545 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
sequential mechanism |
637530, 637539 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
subunit structure, model |
637555 |
| 2.4.2.28 | S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
transition state structure, computational modeling of the transition state, overview |
674184 |
