EC Number   |
Reaction |
Reference |
|---|
    2.4.2.17 | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate |
double displacement mechanism |
637662 |
| 2.4.2.17 | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate |
sequential kinetic mechanism in biosynthetic direction, ordered bi-bi mechanism with ATP binding first to free enzyme and phosphoribosyl-ATP dissociating last from enzyme-product complexes |
637662, 637663, 637670, 637671 |
| 2.4.2.17 | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate |
substrate binding sites, active site structure, switch between active and inactive conformation |
659495 |
| 2.4.2.17 | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate |
substrate binding sites, e.g. Cys104, Asn75, Ser154, Glu156, and Val155, reaction mechanism |
659707 |
