EC Number |
Reaction |
Reference |
---|
2.4.2.10 | orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
mechanism |
489716, 489723, 489728 |
2.4.2.10 | orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
mechanism is bi bi ping pong |
489718 |
2.4.2.10 | orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
ping pong mechanism is not operable, NMR exchange experiments |
489734 |
2.4.2.10 | orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
random sequential kinetic mechanism |
659903 |
2.4.2.10 | orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate |
reaction scheme, half-of-sites binding of orotidine 5-phosphate and alpha-D-5-phosphorylribose 1-diphosphate to the enzyme supports an alternative variant of the Theorell-Chance mechanism with alternating site catalysis, in addition to a ping-pong bi-bi kinetic mechanism, overview |
672162 |