EC Number   |
Reaction |
Reference |
|---|
    2.3.3.9 | acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA |
compulsory-order mechanism, glyoxylate being the first-binding substrate, glyoxylate triggers a conformational change in the enzyme and as a consequence, the correctly shaped binding site for acetyl-CoA is created |
638500 |
| 2.3.3.9 | acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA |
mechanism |
638502, 638507 |
| 2.3.3.9 | acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA |
mechanism: D631 and R338 act in concert to form the enolate anion of acetyl-CoA in the rate limiting step. C617 is oxidized to cysteine-sulfenic acid |
660456 |
| 2.3.3.9 | acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA |
sequencial random mechanism |
638479 |
| 2.3.3.9 | acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA |
sequential bireactant mechanism |
638478 |
