2.1.1.74 | 5,10-methylenetetrahydrofolate + uracil54 in tRNA + NAD(P)H + H+ = tetrahydrofolate + 5-methyluracil54 in tRNA + NAD(P)+ |
catalytic mechanism and active site structure, the methylene of MTHF is directly transferred onto U54, and then the exocyclic methylene of U54 is reduced by FADH2, overview |
706541 |