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Results 1 - 3 of 3
EC Number Reaction Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.166S-adenosyl-L-methionine + uridine2552 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA - -
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.166S-adenosyl-L-methionine + uridine2552 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA a reaction mechanism for the methyltransfer activity of RrmJ is proposed 704404
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.166S-adenosyl-L-methionine + uridine2552 in 23S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA mechanism, based on modeling studies and the structure of the 50S ribosome, a two-step model is proposed where the A loop undocks from the tightly packed 50S ribosomal subunit, allowing RrmJ to gain access to the substrate nucleotide U2552, and where U2552 undergoes base flipping, allowing the enzyme to methylate the 2'-O position of the ribose 704265
Results 1 - 3 of 3