2.1.1.151 | S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III |
the conserved Tyr226 residue in CbiL catalyzes the direct transfer of a methyl group from S-adenosylmethionine to the substrate through an SN2-like mechanism, S-adenosyl-L-homocysteine binds to Pro14, Asp106, Phe109, Ala135, and Val205, as well as to Val104 and Phe136 via a water molecule |
-, 679789 |