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Results 1 - 8 of 8
EC Number Reaction Commentary Reference
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O - -
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O 2 possible catalytic pathways of the reaction, overview, Tyrp274 is catalytically important, the following residues are not important for enzyme activity: Cys167, Tyr135, Tyr160, Tyr170, Tyr213, Tyr240, Tyr276, Trp36, Trp123, Trp166, and Trp198 656175
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O active site structure 656245
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O analysis of catalytic mechanism, modeling of active site structure 654965
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O CPO catalyzes two sequential oxidative decarboxylations of propionate moieties on coproporphyrinogen-III forming protoporphyrinogen-IX through the monovinyl intermediate harderoporphyrinogen 677031
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O reaction mechanism, substrate docking study and binding mode, involving residues H131, R135, D274, and R275, and active site analysis using crystal structures, molecular dynamics simulations, overview. Selectivity of the active site, formed by His131, Asn133, and Ser117, toward substituted tetrapyrroles, nonoccurrence of catalysis on the C and D rings of the tetrapyrrole. The carbonyl oxygen of G276 intervenes in the substrate anchoring by hydrogen bonding of the ring D pyrrole NH group. The pyrrole ring is very unlikely to undergo deprotonation during the catalytic cycle 725779
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O reaction starts by O2 addition to the pyrrole substrate yielding a hydroperoxide, which then abstracts a proton from the reactive propionate substituent, and the reaction may then proceed through H2O elimination, followed by decarboxylation 685536
Show all pathways known for 1.3.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.3.3.3coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O substrate binding at the active site, structure and mechanism, catalytic mechanism 654966
Results 1 - 8 of 8