EC Number   |
Reaction |
Reference |
|---|
   1.14.20.1 | penicillin N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O |
- |
- |
| 1.14.20.1 | penicillin N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O |
bifunctional enzyme, residues W82, N305 and M306 are involved in catalysis, overview |
659322 |
| 1.14.20.1 | penicillin N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O |
ping pong reaction mechanism, analysis, overview |
-, 744318 |
| 1.14.20.1 | penicillin N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O |
presence of a stable iron-peroxo intermediate in equilibrium with a more reactive ferryl species. Formation of CO2 as a leaving group by decarboxylation of 2-oxoglutarate. Substitution of CO2 by the penicillin substrate triggers the oxidation reaction in a booby-trap-like mechanism |
687191 |
| 1.14.20.1 | penicillin N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O |
reaction mechanism |
659719 |
