EC Number |
Reaction |
Reference |
---|
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
- |
- |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
a stable 4a-hydroperoxy-flavin carries out a nucleophilic attack on the ketone |
438968 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
enantioselectivity |
438980, 438988, 438989 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
general mechanistic scheme |
438969, 438979 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
kinetic studies |
438990 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
mechanistic study |
-, 438980, 438982, 438986 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
re-side specificity of cofactor binding, stereochemistry |
438972 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
reaction mechanism |
438982, 438990 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
regioselectivity |
438969, 438980 |
1.14.13.22 | cyclohexanone + NADPH + H+ + O2 = hexano-6-lactone + NADP+ + H2O |
stereochemistry |
438980 |