EC Number |
Reaction |
Reference |
---|
1.14.12.7 | phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ |
mechanism, product formation is tightly coupled to electron delivery, comparison of mechanisms of different dioxygenases |
-, 654770 |
1.14.12.7 | phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ |
mechanism, synergistic effect of substrate and phthalate dioxygenase reductase rendering the enzyme fully catalytically active |
-, 654728 |
1.14.12.7 | phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ |
reduced phthalate dioxygenase reductase first interacts with phthylate dioxygenase and reduces the Rieske [2Fe-2S]center. Phthalate and O2 then bind reversibly and reduced phthalate dioxygenase transfers one more electron to the enzyme |
-, 439047 |