EC Number |
Reaction |
Reference |
---|
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
aldoketoreductase superfamily |
347988, 347989, 347990 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
bi bi mechanism, NADP+ binds to the free enzyme before the hydroxysteroid substrate, the ketosteroid product leaves first, followed by NADPH |
286355 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
bi bi mechanism, pyridine nucleotide binds before substrate |
-, 347981, 347988 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
bi bi mechanism, pyridine nucleotide binds first and leaves last |
347979, 347989, 347990 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
bi bi ordered mechanism, kinetic analysis, overview |
687635 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
binding and release or pyridine is rate-limiting |
347979 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
catalytic triad residues Ser114, Tyr155, and Lys159 have mechanistic roles in the catalytic reaction |
669389 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
ordered and sequential mechanism, nucleotide binds first and leaves last |
-, 347985, 347990 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
ordered bi bi reaction mechanism |
654756 |
1.1.1.213 | a 3alpha-hydroxysteroid + NAD(P)+ = a 3-oxosteroid + NAD(P)H + H+ |
short-chain alcohol/polyol dehydrogenase family |
-, 347986 |