EC Number |
Reaction |
Reference |
---|
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
- |
- |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
active site structure includes an active site tunnel, substrate binding at Asp447 at the protein surface |
675371 |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
catalytic mechanism involving residues Gly734, Cys418 and Cys419, transition state, modeling, overview |
674168 |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
modelling study proposes a four-step mechanism. The reaction is initiated by H transfer from C418 via C410 to the glycyl radical G734. H transfer from C419 to G734 is the rate-limiting process |
662704 |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
part of a bacterial-type mixed-acid fermentation in combination with alcohol dehydrogenase E |
662893 |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
reaction via glycyl radical |
672714 |
2.3.1.54 | acetyl-CoA + formate = CoA + pyruvate |
the reaction mechanism proceeds via generation of a catalytically essential glycyl radical at Gly734 |
671620 |