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EC Number Reaction Commentary Reference
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] analysis of the reaction mechanism via an enzyme-bound intermediate beta-ketoacid pyridoxal-5'-phosphate aldimine, presence of multiple catalytic residues in the Escherichia coli enzyme 673041
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] binding of pimeloyl-CoA causes a conformational change in the active site 487054
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] binding study of L-alanine and D-alanine to the enzyme 487054, 487058
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] detailed catalytic reaction mechanism, overview 676274
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] formation of an external intermediate beta-ketoacid pyridoxal-5'-phosphate aldimine, preference for L-alanine 674626
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] reaction mechanism 487053, 487056, 487057, 487058
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] reaction mechanism could be shared by all alpha-oxoamine synthases 487053
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] reaction mechanism, formation of the pyridoxal-phosphate-stabilized carbanion by abstraction of the C2-H proton of the alanine-pyridoxal-phosphate aldimine, followed by acylation and decarboxylation 487053, 487056
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] Schiff base formation between D- or L-alanine and pyridoxal-5'-phophate in the active site 487054
Show all pathways known for 2.3.1.47Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.47pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein] via an AtbioF-PLP internal aldimine complex, i.e. a Schiff base formed between PLP and a Lys residue in the protein 676580
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