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EC Number Reaction Commentary Reference
Show all pathways known for 1.3.8.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.8.52-methylbutanoyl-CoA + electron-transfer flavoprotein = (E)-2-methylbut-2-enoyl-CoA + reduced electron-transfer flavoprotein + H+ - -
Show all pathways known for 1.3.8.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.8.52-methylbutanoyl-CoA + electron-transfer flavoprotein = (E)-2-methylbut-2-enoyl-CoA + reduced electron-transfer flavoprotein + H+ reaction mechanism determining substrate specificity 656162
Show all pathways known for 1.3.8.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.8.52-methylbutanoyl-CoA + electron-transfer flavoprotein = (E)-2-methylbut-2-enoyl-CoA + reduced electron-transfer flavoprotein + H+ the isovaleryl-CoA dehydrogenase 1, i.e. IVD1, EC 1.3.99.10, from Solanum tuberosum shows maximal activity with 2-methylbutyryl-CoA, the binding pockets of 2-methylbutyryl-CoA and isovaleryl-CoA dehydrogenase are nearly identical, the enzyme therefore shall also be classified to EC 1.3.99.12, active site structure, residues Met361, Ala365, Val88, Val92, and Val96 are involved in catalysis 656288
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