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Posttranslational Modification
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3.2.1.143
proteolytic modification
PARG59 expression constructs with amino acids encoded by exon 4 at the N-terminus are targeted to the mitochondria. Deletion and missense mutants allow identification of a canonical N-terminal mitochondrial targeting sequence consisting of the first 16 amino acids encoded by PARG exon 4. Sub-mitochondrial localization experiments indicate that this mitochondrial PARG isoform is targeted to the mitochondrial matrix
708414
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