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EC Number
Posttranslational Modification
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Reference
3.1.3.36
phosphoprotein
centrosomal kinase AURKA phosphorylates INPP5E and thereby increases its 5-phosphatase activity
751178
3.1.3.36
phosphoprotein
phosphorylation site: NPXY motif C-terminal to the active site and tyrosine residue 1162 which is also located toward the C-terminus. Epidermal growth factor receptor-stimulates tyrosine phosphorylation of SHIP2 which correlates with increased SHIP2 5-phosphatase activity. This effect is demonstrated in HeLa cells
678074
3.1.3.36
phosphoprotein
SHIP1 is localized to the membrane and is tyrosine phosphorylated during cell adhesion
732476
3.1.3.36
phosphoprotein
tyrosine phosphorylation is induced by CD32a cross-linking
679145
3.1.3.36
phosphoprotein
upon intracerebroventricular treatment with insulin, 5ptase IV undergoes a time-dependent tyrosine phosphorylation. Treatment with a phosphorthioate-modified antisense oligonucleotide for 5ptase IV shows a 70% reduction of insulin induced tyrosine phosphorylation of 5ptase IV and an increase in basal accumulation of phosphorylated inositols in the hypothalamus
679517
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