EC Number   |
Posttranslational Modification |
Reference |
|---|
   3.1.1.61 | phosphoprotein |
- |
666386 |
| 3.1.1.61 | phosphoprotein |
enzyme is activated in vivo by phosphorylation of a single aspartate, Asp56, in its regulatory domain |
646058 |
| 3.1.1.61 | phosphoprotein |
In its unphosphorylated state, the regulatory domain inhibits enzyme activity of effector domain. Phosphorylation of the regulator domain leads to an enhancement of enzyme activity through a relief of inhibition and a stimulatory effect on catalysis. |
646059 |
| 3.1.1.61 | phosphoprotein |
phosphorylation by phosphoramidate requires Mg2+, phosphorylation of the regulatory domain at Asp-56 results in a reorganization of the domain interface, allowing exposure of the active site to the receptor substrate and simultaneously stimulating methylesterase activity |
646052 |
| 3.1.1.61 | phosphoprotein |
phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of enzyme |
646057 |
| 3.1.1.61 | phosphoprotein |
the regulation of activity of methylesterase CheB via phosphorylation is central to chemotactic adaption |
666389 |
