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EC Number
Posttranslational Modification
proteolytic modification
autocatalytic cleavage, cleavage sites are Lys694-Phe695 and Thr581-Phe582, following incubation at 37C for 16 h, ADAMTS-4 is detected as isoforms of 68000 Da, 53000 Da and 40000 Da
proteolytic modification
in vivo production of proteolytically active ADAMTS-4 requires removal of the prodomain by a furin-like activity and MMP-mediated removal of a portion of the C-terminal spacer domain
Results 1 - 2 of 2