EC Number   |
Application |
Reference |
|---|
    4.3.2.9 | medicine |
enzyme overexpression defines a subgroup of breast tumors with poor clinical outcome. The enzyme is a cancer biomarker and a serological marker |
720332 |
| 4.3.2.9 | medicine |
gamma-glutamylcyclotransferase is a target molecule for cancer diagnosis and treatment |
735747 |
| 4.3.2.9 | medicine |
GGCT silencing significantly suppresses proliferation of colorectal cancer cells and arrests cell cycle at the G0/G1 phase by regulating the expression of p21, p27, and cyclin E. GGCT silencing triggers the apoptosis of colorectal cancer cells by activating caspase-3 and cleaved poly-ADPribose polymerase pathways and downregulating the phosphorylation proline-rich Akt substrate of 40 kDa (PRAS40) expression levels. GGCT silencing combined with 5-fluorouracil treatment further induces the apoptotic rate of colorectal cancer cells |
741612 |
| 4.3.2.9 | medicine |
in patients with gastrointestinal fistula, levels of alkaline phosphatase and gamma-glutamylcyclotransferase increase significantly on the third day after beginning of enteral feeding and decrease gradually afterwards. The longer the total parenteral nutrition lasted, the more severe the enteral refeeding syndrome becomes. Early enteral nutrition is useful in preventing it |
673099 |
