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EC Number Application Commentary Reference
Show all pathways known for 4.1.1.65Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.65analysis development of a fluorescence-based assay for selectively monitoring production of phosphatidylethanolamine in reactions using a maltose-binding protein fusion with Plasmodium knowlesi PSD as the enzyme. The product detection by fluorescence occurs after the lipid reacts with a water-soluble distyrylbenzene-bis-aldehyde and provides strong discrimination against the phosphatidylserine substrate. The assay is amenable to application in 96- and 384-well microtiter plates -, 748230
Show all pathways known for 4.1.1.65Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.65analysis use of the complementation of a Saccharomyces cerevisiae mutant for screening inhibitors 748688
Show all pathways known for 4.1.1.65Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.65medicine phosphatidylserine decarboxylase PISD is downregulated by 8fold in migratory cells. Breast cancer cells overexpressing PISD exhibit reduced tumor-initiating potential in a high-throughput microfluidic mammosphere device and mouse xenograft model 749364
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