Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Application

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 2 of 2
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.46synthesis construction of an artificial pathway for muconic acid production in Escherichia coli by connecting 2,3-dihydroxybenzoic acid biosynthesis with its degradation pathway. Overexpression of entCBA and the key enzymes in the shikimate pathway leads to the production of 900 mg/l of 2,3-dihydroxybenzoic acid. Expression of 2,3-dihydroxybenzoic acid decarboxylase coupled with catechol 1,2-dioxygenase achieves the conversion of 2,3-dihydroxybenzoic acid into muconic acid. Assembly of the total pathway results in the de novo production of muconic acid up to 480 mg/l 747588
Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.46synthesis development of an artificial pathway in Escherichia coli for the biosynthesis of muconic acid. Expression of 2,3-dihydroxybenzoate decarboxylase and catechol 1,2-dioxygenase and metabolic optimization by increasing the flux from chorismate through the enterobactin biosynthesis pathway and by regulating the shikimate pathway leads to synthesis of 605.18 mg/l of muconic acid from glucose in a shaking flask culture -, 748349
Results 1 - 2 of 2