EC Number   |
Application |
Reference |
|---|
    3.5.1.19 | analysis |
determination of nicotinamide |
246577 |
| 3.5.1.19 | analysis |
nicotinamidases are key analytical biocatalysts for screening modulators in relevant biomedical enzymes, such as sirtuins and poly-ADP-ribosyltransferases |
753679 |
| 3.5.1.19 | drug development |
enzyme is involved in the activation of the antituberculosis drug pyrazinamide |
679806 |
| 3.5.1.19 | drug development |
while nicotinamidases are widespread in nature they are not occuring within mammals and present a potential drug target. The enzymes can be used in the activation of tuberculosis prodrugs such as pyrazinamide |
734741 |
| 3.5.1.19 | medicine |
Riemerella anatipestifer AS87_01735 gene encodes PncA, which is an important virulence factor. The Yb2DELTApncA mutant can be used as a novel live vaccine candidate |
-, 752546 |
| 3.5.1.19 | medicine |
the absence of nicotinamidase in humans makes it a promising drug target |
753679 |
