EC Number |
Application |
Reference |
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3.4.24.19 | medicine |
procollagen C-proteinase inhibition may be a suitable target for the reduction of hypertrophic scarring |
690203 |
3.4.24.19 | medicine |
secreted Frizzled-related protein sFRP2 serves as a direct enhancer of procollagen C proteinase activity of tolloid-like metalloproteinases. The level of fibrosis, in which procollagen processing by tolloid-like proteinases has a rate-limiting role, is markedly reduced in Sfrp2-null mice subjected to myocardial infarction. This reduced level of fibrosis is accompanied by significantly improved cardiac function |
700348 |
3.4.24.19 | medicine |
the serum procollagen C-proteinase enhancer 1 glycopattern is associated with the physiological and pathological states of bone |
711771 |
3.4.24.19 | more |
involved in deposition of collagen fibrils in the extracellular matrix following processing of procollagen propeptides, dorsoventral patterning through cleavage of chordin, collagen and elastin cross-linking by processing of inactive precursors of lysyl oxidases, proteoglycan maturation and assembly of the dermal-epidermal junction by processing of laminin 5 chains and cleaving the C-propeptide of type VII procollagen |
668838 |