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Results 1 - 3 of 3
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43diagnostics the enzyme is a potential marker for certain colon tumors and breast cancer 668763
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43medicine mammalian protease cathepsin V is a therapeutic target to inhibit TLR4-mediated inflammation induced by extracellular high-mobility group box 1 (HMGB1) (disulfide form). HMGB1 (disulfide form), via activation of toll-like receptor 4 (TLR4)-dependent signaling, is a strong driver of pathologic inflammation in both acute and chronic conditions. The mechanism of action involves a direct interaction between cathepsin V with TLR4 and its adaptor protein MyD88 754753
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43medicine studies on the role of cathepsin V and cystatin C in the pathophysiology aortic stenosis 683107
Results 1 - 3 of 3