EC Number |
Application |
Reference |
---|
3.4.22.32 | agriculture |
a concentration of 0.0003 mM of bromelain is sufficient for 90% growth inhibition of Fusarium verticillioides. Bromelain also inhibits the growth of Fusarium oxysporum f. sp. melonis and Fuarium proliferatum. The enzyme shows a potential use as an effective agent for crop protection |
732431 |
3.4.22.32 | food industry |
stem bromelain immobilized on chitosan beads without glutaraldehyde yields a food-safe biocatalyst for unstable real wine future application |
731526 |
3.4.22.32 | food industry |
the immobilized stem bromelain has productive biotechnological applications in wine-making |
731838 |
3.4.22.32 | medicine |
bromelain exhibits various fibrinolytic, anti-edematous, anti-thrombotic, and anti-inflammatory activities supporting its application for many therapeutic benefits. Effects of bromelain on the pro-wound healing activities and the regenerative properties of mesenchymal stem cells. The combined use of bromelain and dexamethasone sodium phosphate stimulated the pro-wound healing activities and the regenerative properties of mesenchymal stem cells better than bromelain and dexamethasone alone |
754265 |
3.4.22.32 | medicine |
bromelain from pineapple stem shows therapeutic benefits in a variety of inflammatory diseases, including murine inflammatory bowel disease, mechanism, overview. Bromelain primary long-term effect is abrogation of firm adhesion of leukocytes to blood vessels at the site of inflammation. These changes in adhesion are correlated with rapid re-expression of the bromelain-sensitive CD62L/L-selectin molecules that mediate rolling following in vivo bromelain treatment and minimal re-expression of CD128 |
697421 |
3.4.22.32 | medicine |
bromelain has anti-cancer activity, as well as antithrombotic, fibrinolytic, antiedematous, and burn debridement properties |
707968 |
3.4.22.32 | medicine |
bromelain has antitumoral activity |
682476 |
3.4.22.32 | medicine |
bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities |
753631 |
3.4.22.32 | medicine |
bromelain possesses anti-inflammatory activity and reduces blood viscosity, prevents the aggregation of blood platelets, and improves ischemia-reperfusion injury, I/R, in a skeletal muscle model in adult Sprague-Dawley rats. The enzyme increases phosphorylation of Akt in rat heart both in the cytosolic and the nuclear fraction following I/R |
677476 |
3.4.22.32 | medicine |
bromelain relieves osteoarthritis. Bromelain is used as an adjuvant therapeutic approach in the treatment of chronic inflammatory, malignant, and autoimmune diseases. Bromelain prevents or minimizes the severity of angina pectoris and transient ischemic attack. Bromelain influences blood coagulation by increasing the serum fibrinolytic ability and by inhibiting the synthesis of fibrin. Bromelain counteracts some of the effects of certain intestinal pathogens like Vibrio cholera and Escherichia coli, whose enterotoxin causes diarrhea. The anticancerous activity of bromelain is due to its direct impact on cancer cells and their microenvironment, as well as on the modulation of immune, inflammatory, and haemostatic systems. Bromelain is used for treating acute inflammation and sports injuries. Bromelain applied as a cream (35% bromelain in a lipid base) can be beneficial for debridement of necrotic tissue and acceleration of healing |
731527 |