EC Number   |
Application |
Reference |
|---|
   3.4.21.119 | analysis |
substrate substrate ABZ-Val-Arg-Phe-Arg-Ser-Thr-Gln-Tyr(3-NO2)-NH2 is suitable for determination of KLK13 activity and is successfully converted into an activity-based probe by the incorporation of a chloromethylketone warhead and biotin bait. The modified subvsrtae is applicable in complex biological samples |
753922 |
| 3.4.21.119 | diagnostics |
gene KLK13 mRNA expression constitutes a biomarker for the prediction of overall survival in nonsmall cell lung cancer and that its quantitative assessment in tumor tissues can aid in treatment decision making. Kaplan-Meier survival analyses demonstrate that patients with KLK13-positive tumors survive significantly longer than those with KLK13-negative ones |
732966 |
| 3.4.21.119 | diagnostics |
loss of the enzyme is a potential biomarker for early detection of lymph node metastasis in oral squamous cell carcinoma cell lines |
732498 |
| 3.4.21.119 | diagnostics |
the enzyme has clinical importance as a favorable prognostic biomarker for gastric cancer patients' survival |
732961 |
| 3.4.21.119 | medicine |
a multiparametric panel of kallikrein markers for lung cancer diagnosis with relatively good accuracy is provided |
697372 |
| 3.4.21.119 | medicine |
although marginally significant, patients with high KLK13 expression at the mRNA or protein level have lower overall survival |
691155 |
| 3.4.21.119 | medicine |
gene may be involved in the pathogenesis and/or progression of breast cancer and may find applicability as cancer biomarker |
647373 |
| 3.4.21.119 | medicine |
hK13 is one of the important kallikreins in skin physiology |
669753 |
| 3.4.21.119 | medicine |
most salivary gland tumors show high levels of enzyme expression. Pleomorphic adenoma shows less staining than normal tissue, adenoid cystic carcinomas, polymorphous low grade adenocarcinomas and adenocarcinomas not otherwise specified stain significantly more than normal salivary gland tissue |
668974 |
| 3.4.21.119 | medicine |
patients with ovarian carcinoma, women with enzyme-positive tumors most often have early stage disease, no residual tumor after surgery and optimal debulking success. Patients with enzyme-positive tumors have a significantly longer progression-free survival and overall survival. Use of enzyme as biomarker for ovarian carcinoma |
669632 |
