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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.41biotechnology use of enzyme as probe of membrane sphingomyelin 652708
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.41medicine a molecular mechanism for Loxosceles venom nephrotoxicity is demonstrated that is dependent on the catalytic activity of phospholipase-D toxin 691130
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.41medicine recombinant SMase D can replace venom for anti-venom production and therapy 690391
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.41medicine SMaseD induces apoptosis in human keratinocytes, which is associated with an increased expression of metalloproteinase-2 and -9. The use of metalloproteinase inhibitors, such as tetracycline, may prevent cell death and potentially may prevent tissue destruction after envenomation 665951
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