EC Number   |
Application |
Reference |
|---|
   3.1.3.12 | agriculture |
possible use of OsTPP1 in abiotic stress engineering of crops |
694776 |
| 3.1.3.12 | biotechnology |
The transformation of rice plants with a gene that encodes a bifunctional fusion enzyme of trehalose-6-phosphate synthase and phosphatase from Escherischia coli increases the trehalose levels in these plants, shows no visible growth inhibition. The production of trehalose in these plants results in increased tolerance to drought, salt, and cold stresses. |
653540 |
| 3.1.3.12 | drug development |
Bm-TPP bodes well as a rational drug target against lymphatic filariasis |
713683 |
| 3.1.3.12 | drug development |
enzyme MtbTPP (OtsB2) is considered a promising potential target for discovery of antimicrobial drugs |
-, 750507 |
| 3.1.3.12 | medicine |
enzyme may serve as a potential target for antifungal drugs |
651481 |
| 3.1.3.12 | medicine |
immunization of Mastomys coucha with Brugia (B.) malayi trehalose-6-phosphate phosphatase confers considerable protection against B. malayi establishment by engendering a long-lasting effective immune response and therefore emerges as a potential vaccine candidate against lymphatic filariasis |
730747 |
| 3.1.3.12 | medicine |
may be a candidate for vaccine development for the control of tuberculosis |
-, 679880 |
| 3.1.3.12 | medicine |
the enzyme can play a key role in the biosynthesis of trehalose compounds, such as trehalose mycolates, and may represent an excellent target site for chemotherapy against tuberculosis and other mycobacterial diseases |
652396 |
