2.7.2.15 | biotechnology |
in order to realise an efficient production of 1-propanol through amino acid biosynthetic pathway using glucose or glycerol as a carbon source L-threonine overproducing strain, TH20 is employed as a base strain and engineered to establish a novel pathway leading to the formation of1-propanol under aerobic condition. The engineered strain, PRO2, harbouring a plasmid overexpressing the atoDA, adhEmut, thrABC, ackA and cimA genes is able to produce more than 10 g/L of 1-propanol from glucose or glycerol in aerobic fed-batch fermentation |
723093 |