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Results 1 - 3 of 3
EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.82synthesis a route for the production of GABA via putrescine in Corynebacterium glutamicum. A putrescine-producing recombinant Corynebacterium glutamicum strain is converted into a GABA producing strain by heterologous expression of putrescine transaminase PatA and gamma-aminobutyraldehyde dehydrogenase PatD genes from Escherichia coli. The resultant strain produces 5.3 g per l of GABA. GABA production is improved further by adjusting the concentration of nitrogen in the culture medium, by avoiding the formation of the by-product N-acetylputrescine and by deletion of the genes for GABA catabolism and GABA re-uptake. GABA accumulation by this strain is increased by 5% to 8.0 g per l, and the volumetric productivity is increased to 0.31 g per l and h 737428
Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.82synthesis enzyme prefers diaminoalkanes as substrates and thereby generates cyclic imines from the omega-amino aldehyde intermediates. The addition of a mild chemical reducing agent rapidly reduces the imine intermediate in situ to furnish a range of N-heterocycle products -, 738065
Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.82synthesis putrescine transaminase Pp-SpuC application in the transamination of a comprehensive range of ketones/aldehydes for the production of a variety of benzylamine derivatives. Applications of enzyme Pp-SpuC as a biocatalyst with broad substrate tolerance -, 759219
Results 1 - 3 of 3