EC Number |
Application |
Reference |
---|
2.6.1.76 | medicine |
- |
288732 |
2.6.1.76 | medicine |
drug development, Acinetobacter sp. can be part of the normal flora of human skin but also of opportunistic infections like septicemia, pneumonia, endocarditis, meningitis, skin and wound sepsis or urinary tract infections, clinically important isolates show widespread and increasing resistance to many commonly used antibiotics |
-, 288731 |
2.6.1.76 | medicine |
responsible for many human infections including otitis media, meningitis, epiglottis and pneumonia |
288732 |
2.6.1.76 | synthesis |
production of ectoine in Escherichia coli. The Escherichia coli regulatory protein AraC is engineered to recognize ectoine as it snon-natural effector and to activate transcription upon ectoine binding. The ectoine biosynthetic cluster from Halomonas elongata is cloned into Escherichia coli. By engineering the rate-limiting enzyme L-2,4-diaminobutyric acid aminotransferase EctB, ectoine production and the specific activityof the EctB mutant are increased |
-, 738983 |