EC Number   |
Application |
Reference |
|---|
  2.3.1.71 | medicine |
in a small cohort of South African Caucasian individuals, the two most prominent GLYAT haplotypes in all populations analysed, are S156 (70%) and T17S156 (20%). The S156C199 and S156H131 haplotypes, which have a negative effect on the enzyme activity of a recombinant human GLYAT, are detected at very low frequencies. An additional Q61L SNP occurring at a high frequency (12%) was detected |
736179 |
| 2.3.1.71 | medicine |
isoform Glyat expression is suppressed in all hepatocellular carcinomas, but not in other liver diseases. Glyat repression in cancerous cells in the liver is controlled at the transcriptional level |
718757 |
| 2.3.1.71 | medicine |
study to investigate 4-aminobenzoic acid as an alternative glycine conjugation probe. All of the participants were homozygous for increased enzyme activity, but excretion of product 4-amino-N-benzoylglycine varies significantly (16-56%, hippurate ratio) |
736376 |
