EC Number |
Application |
Reference |
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2.3.1.67 | analysis |
procedure for identification of LPCAT2-specific inhibitors via high-throughput screening |
736604 |
2.3.1.67 | drug development |
identification of LPCAT2-specific inhibitors in order to ameliorate PAF-related inflammatory diseases, fluorescence-based high-throughput library screening |
736604 |
2.3.1.67 | medicine |
inhibitors 3-decanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone and 2-methoxy-5-methyl-3-tetradecanoyloxy-1,4-benzoquinone at 2.5 mg/kg shod significant, 47.9-51.7%, inhibition in the carrageenan-induced mouse paw edema test, stronger than that of prednisolone at 10 mg/kg |
735644 |
2.3.1.67 | medicine |
metabolic role in inflammatory disorders using experimental allergic encephalomyelitis (EAE), an animal model for multiple sclerosis (MS) |
688161 |
2.3.1.67 | medicine |
study on the impact of diet on platelet-activating factor metabolism. Platelet-activating factor is inversely correlated with antioxidant-rich foods (herbal drinks and coffee), the dietary antioxidant capacity as well as a dietary pattern characterized by legumes, vegetables, poultry and fish. Platelet-activating factor is positively correlated to percentage of fat intake. Lyso-PAF acetyltransferase is also negatively associated with healthy patterns (fruits, nuts and herbal drinks, and a pattern rich in olive oil and whole-wheat products), as well as the dietary antioxidant capacity and percentage of monounsaturated fatty acids |
736060 |
2.3.1.67 | medicine |
the results increases the understanding of the clinical implications of platelet-activating factor inhibition with regard to HIV infection |
701601 |