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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.45analysis methods for assaying the activity of sialate-O-acetyltransferases are presented 686986
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.45analysis the non-radioactive ELISA can quickly detect sialate-O-acetyltransferase, and thus, may become a suitable tool for acute lymphoblastic leukemia-monitoring in larger scale 686985
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.45medicine high level of SOAT activity in lymphoblasts of childhood acute lymphoblastic leukaemia (ALL) is detected. SOAT in cell lysates or microsomal fractions of lymphoblasts of patients is up to 22fold higher than in healthy donors. SOAT activity increases at the diagnosis of leukaemia, decreases with clinical remission and sharply increases again in relapsed patients as determined by radiometric-assay. A newly developed non-radioactive ELISA can quickly detect SOAT, and serves as tool for ALL-monitoring in larger scale 686985
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