EC Number   |
Application |
Reference |
|---|
    1.1.1.44 | agriculture |
when temperature-stable forms of of the enzyme (PGD1 and PGD2) are expressed in maize endosperm plastids, this increases enzyme activity and mitigates the reduction in grain yield that occurred in control plants exposed to elevated temperatures at night. This genetic improvement could be included as part of integrated approaches to mitigate yield losses due to climate change |
762293 |
| 1.1.1.44 | biotechnology |
immobilization of 6PDGH on ASMNPs can be an effective way for its biotechnological and biosensor applications |
762260 |
| 1.1.1.44 | medicine |
- |
286839, 286903 |
| 1.1.1.44 | medicine |
6-phosphogluconate dehydrogenase is a potential target for new drugs against African trypanosomiasis |
686656 |
| 1.1.1.44 | medicine |
6PGDH might be a target for chemotherapy against parasitic infections as trypanosomiasis |
286903 |
| 1.1.1.44 | medicine |
with a deficiency of 6-phosphogluconate dehydrogenase some reticulocytosis occurs |
286837 |
| 1.1.1.44 | more |
the enzyme can be used for power production in biobatteries. Mutant N32E/R33I/T34I versus the wild-type 6PGDH are evaluated electrochemically in an anodic reaction system containing two enzymes: 6PGDH and diaphorase, a coenzyme (NADP+ or NAD+), an electron mediator AQDS, and a 6-phosphogluconate substrate. Cyclic voltammetry results clearly show that both enzymes produce significant oxidation current peaks at -0.3 V versus Ag/AgCl. The mutant N32E/R33I/T34I exhibits a current density 25% higher than that generated by the wild-type |
743823 |
| 1.1.1.44 | pharmacology |
the enzyme is a target for inhibitor development for usage as drugs against African Trypanosomiasis |
656751 |
| 1.1.1.44 | synthesis |
NADPH regeneration. When coupled with glucose-6-phosphate dehydrogenase the enzyme generates two moles of NADPH per mole of glucose-6-phosphate |
-, 748598 |
| 1.1.1.44 | synthesis |
thermostability may lead to some practical applications |
-, 286836 |
