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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.300medicine enzyme is associated with retinal dystrophy and encodes an enzyme with unique, nonredundant role in the photoreceptor cells 656851
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.300medicine transfection with retinol dehydrogenase 12 protects cells against nonanal-induced toxicity but is ineffective against 4-hydroxynonenal. 4-Hydroxynonenal strongly inhibits the activities of lecithin:retinol acyl transferase and aldehyde dehydrogenase, resulting in decreased levels of retinyl esters and retinoic acid and accumulation of unesterified retinol 685381
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.300pharmacology enzyme RDH8 is a therapeutic target for controlling bis-retinoid A2E cytotoxicity 761323
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