EC Number |
Application |
Reference |
---|
3.4.24.B6 | medicine |
critical role of MMPs in the processing and maturation of the dental matrix |
668499 |
3.4.24.B6 | pharmacology |
enzyme is a potential target for selective inhibition and inhibitor design |
652736 |
3.4.24.B6 | medicine |
first report of a homozygous mutation in the MMP-20 gene, the mutation destroys the splice acceptor sequence at the 3' end of intron 6 encoding the hemopexin domain, the enamel of the subjects' teeth is pigmented, its surface mottled and rough and the enamel layer more opaque than the underlying dentine |
669815 |
3.4.24.B6 | more |
MMP-20 acts either directly or indirectly to faciliate the removal of maturation-stage enamel proteins |
-, 669647 |
3.4.24.B6 | more |
MMP-20 expression is primarly confined to tooth tissue |
667722 |
3.4.24.B6 | degradation |
MMP-20 processes dentin sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis |
669508 |
3.4.24.B6 | medicine |
study on the hypothesis that MMP-20 is overexpressed in the dentin-enamel junction, dentin-pulp complex components, and carious dentin of patients that head-and-neck radiotherapy. No apparent damage to the dentin-enamel junction microstructure or other dentin-pulp complex components is observed and no statistically significant differences are detected in MMP-20 expression between the irradiated and control groups |
753160 |